Use of heavy Trypan blue in macular hole surgery

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Cystoid macular oedema with trypan blue use.

We present a large comparative series of trypan blue use in cataract surgery. This series of trypan blue used in all eyes regardless of cataract severity may be unique. We found an apparent increased rate of cystoid macular oedema (CMO) associated with trypan blue use. Melles et al’s report on the use of trypan blue in cataract extraction in 1999 combined with Apple et al’s series on dye enhanc...

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[Evaluation of trypan-blue toxicity in macular hole surgery with electroretinography].

PURPOSE Concern has been raised about the retinal toxicity of vital dyes. We designed a prospective study to determine the possible toxicity of trypan-blue (TB) in macular hole surgery with TB-assisted internal limiting membrane (ILM) peeling through the performance of electroretinograms (ERGs). METHODS Patients diagnosed with a macular hole underwent ophthalmological evaluation prior to surg...

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Histopathological analysis in experimental macular surgery with trypan blue.

AIM To analyse the effect of trypan blue on the retina in an experimental setting of macular surgery. METHODS Porcine eyes were used within 3 hours after death. The eyes were hemisected and the vitreous removed. Trypan blue (0.15%) was applied over the trephined posterior pole, whereas the rest of the eye cup was filled with a balanced salt solution (BSS). The dye and the BSS were removed aft...

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Progressive atrophy of retinal pigment epithelium after trypan-blue-assisted ILM peeling for macular hole surgery

We report a case of progressive atrophy of the retinal pigment epithelium (RPE) after trypan-blue-assisted peeling of internal limiting membrane (ILM) for macular hole surgery. A 68-year-old Caucasian female underwent a 20-g pars plana vitrectomy for a chronic stage-3 macular hole. The ILM was stained with 0.06% trypan blue (VisionBlue™, DORC Netherlands) for 2 min after fluid air exchange. Dye...

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A comparison of outcomes after indocyanine green and trypan blue assisted internal limiting membrane peeling during macular hole surgery.

AIMS To compare the anatomical and visual outcomes of macular hole repair surgery using indocyanine green (ICG) or trypan blue (TB) staining of the internal limiting membrane (ILM). METHOD Retrospective analysis of 37 eyes from 37 consecutive patients with stage 2, 3, and 4 idiopathic macular holes who underwent macular hole repair by one surgeon using the same technique but utilising differe...

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ژورنال

عنوان ژورنال: Eye

سال: 2010

ISSN: 0950-222X,1476-5454

DOI: 10.1038/eye.2010.3